Sharpen
Sharpen
BUNDLE & SAVE
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Sharpen
Benefits
Benefits
- Encourages long-term cognitive wellness
- Maintains brain health as you age
- Provides memory support
- Promotes aspects of focus and performance
Key ingredients
Key ingredients
The five key ingredients in Sharpen are Taurine (1000mg), Choline (200mg), Vitamin B6 (1.7mg), L-methylfolate (400mcg DFE), and Vitamin B12 (2.4mcg)
Suggested use
Suggested use
Take two capsules daily, with food. Consider starting with one capsule per day and progressively increasing your dose. For best results, take for a minimum for six months and beyond. Each 30-day supply includes 60 capsules.
9 major allergen free
Endotoxin-free
No Preservatives
Vegan
Non-GMO
Gluten free
9 major allergen free
Endotoxin-free
No Preservatives
Vegan
Non-GMO
Gluten free
9 major allergen free
Endotoxin-free
No Preservatives
Vegan
Non-GMO
Gluten free
9 major allergen free
Endotoxin-free
No Preservatives
Vegan
Non-GMO
Gluten free
9 major allergen free
Endotoxin-free
No Preservatives
Vegan
Non-GMO
Gluten free
9 major allergen free
Endotoxin-free
No Preservatives
Vegan
Non-GMO
Gluten free
Optimize brain health at a cellular level
Encourage long-term cognitive wellness
By providing evidence-based ingredients that help strengthen multiple aspects of cognition, including memory
Maintains brain health as you age
Homocysteine, a marker of brain health, reflects the activity of vitamins B6, B9 (folate), and B12
Provides memory support
Choline is a precursor to acetylcholine, a neurotransmitter that play critical roles in learning and memory
Promote aspects of focus and performance
By supporting the nervous system and neuronal communication
Trusted ingredients
Our pursuit for living healthier, longer is only matched by our relentless pursuit for quality. If an ingredient doesn’t meet our standards, we don’t use it.
- Formulated by scientists
- Ingredients backed by peer-reviewed research
- Premium-quality, lab-tested ingredients
- Third-party safety certified
Research-based ingredients
Our formulations are made with a powerful combination of ingredients that have been shown in research studies to promote longevity and improve healthspan.
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Taurine
Benefits:
- Supports overall brain health
- Improves lifespan and healthspan in mammals
- Boosts cognitive function and performance
- Stimulates new brain cell formation
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Choline
Benefits:
- Enhances working and verbal memory
- Promotes focus and cognitive performance
- Linked to an improvement in brain fog
- Precursor to the neurotransmitter acetylcholine
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Vitamin B6
Benefits:
- Boosts memory in healthy elderly adults
- Lowers a risk factor for dementia
by decreasing homocysteine levels - Promotes a healthy nervous system
- Supports synthesis of key neurotransmitters
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L-Methylfolate
Benefits:
- Decreases oxidative stress
- Relates to superior cognitive test scores
- Lowers a risk factor for dementia
by decreasing homocysteine levels - Active, brain-permeable form of folate
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Vitamin B12
Benefits:
- Strengthens cognition
- Lowers a risk factor for dementia
by decreasing homocysteine levels - Neuroprotective for the nervous system
- Supports brain oxygenation
Scientific references
- Bae et al. The Development of Taurine Supplementary Menus for the Prevention of Dementia and Their Positive Effect on the Cognitive Function in the Elderly with Dementia. Advances in Experimental Medicine and Biology 2019
- Knott et al. Neurocognitive effects of acute choline supplementation in low, medium and high performer healthy volunteers. Pharmacology Biochemistry and Behavior 2015
- Deijen et al. Vitamin B-6 supplementation in elderly men: effects on mood, memory, performance and mental effort. Psychopharmacology 1992
- Stahl. L-methylfolate: a vitamin for your monoamines. The Journal of Clinical Psychiatry 2008
- Ueno et al. Influences of Vitamin B12 Supplementation on Cognition and Homocysteine in Patients with Vitamin B12 Deficiency and Cognitive Impairment. Nutrients 2022
- Smith et al. Homocysteine and Dementia: An International Consensus Statement. Journal of Alzheimer's Disease 2018
- Wurtman and Melamed. Precursor control of neurotransmitter synthesis. Pharmacological Reviews 1980
- Naber et al. Improved human visuomotor performance and pupil constriction after choline supplementation in a placebo-controlled double-blind study. Scientific Reports 2015
- Chen et al. Roles of taurine in cognitive function of physiology, pathologies and toxication. Life Sciences 2019
- Singh et al. Taurine deficiency as a driver of aging. Science 2023
- Gebara et al. Taurine increases hippocampal neurogenesis in aging mice. Stem Cell Research 2015
- Monastero and Baschi. Persistent Cognitive Dysfunction in a Non-Hospitalized COVID-19 Long-Hauler Patient Responding to Cognitive Rehabilitation and Citicoline Treatment. Brain Sciences 2023
- Calderón-Ospina and Orlando Nava-Mesa. B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin. CNS Neuroscience & Therapeutics 2020
- Parra et al. Vitamin B6 and Its Role in Cell Metabolism and Physiology. Cells 2018
- Cagnacci et al. Folate administration decreases oxidative status and blood pressure in postmenopausal women. European Journal of Nutrition 2015
- Morris et al. Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors. The American Journal of Clinical Nutrition 2010
- Sicińska et al. Supplementation with [6S]-5-methyltetrahydrofolate or folic acid equally reduces serum homocysteine concentrations in older adults. International Journal of Food Sciences and Nutrition 2018
- Lee et al. Role of vitamin B12 and folic acid in treatment of Alzheimer's disease: a meta-analysis of randomized control trials. Aging (Albany NY) 2024
- Didangelos et al. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients 2021
- Green. Vitamin B12 deficiency from the perspective of a practicing hematologist. Blood 2017